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While GIP alone has limited therapeutic use in T2DM due to impaired responsiveness, combining GIP agonism with GLP-1 activity produces synergistic metabolic effects in medications that have dual effects, such as tirzepatide

Underlying Conditions Tumors, metabolic issues, or even the somogyi effect (more commonly discussed in diabetes) could also play a role

Its the feel good hormone that motivates folks to engage in gratifying activities, like scarfing down a box of cookies or indulging in a little nooky

I recommend completing your first injection during daylight hours when you feel alert and calm

Kung et al., 2008)

2010;298:R1475R1484