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Since 1997, she was treated at various points with valproate, risperidone, and olanzapine for mood stabilization, along with sertraline and later venlafaxine for depressive symptoms
Although GLP-1 RAs have demonstrated cardiovascular risk reduction in patients with diabetes, these effects were not reported in these obesity trials yet

Phentermine combinations have been used for enhanced appetite suppression, though this requires medical supervision

Some participants began at 2 mg and escalated slowly

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