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Patient preference: Some people are more comfortable with daily routines or are uneasy about having a medication active in their system for a full week

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The hunger regulation can lead to altered food preference and reduced caloric consumption
Review describing the physiological role of GLP-1 in the central regulation of feeding behaviour, as well the effects of pharmacological stimulation of GLP-1 pathways leading to alterations in CNS activity, reduced food intake and weight loss in obesity and T2DM

Watch: doctors explain why GLP-1 patches don't work A medical breakdown of how GLP-1 medications work, why the skin barrier prevents transdermal delivery of peptide drugs, and what the evidence actually says about OTC weight-loss patches marketed with GLP-1 branding
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