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7 Furthermore, a 12-week study in adults with prediabetes demonstrated that daily allulose supplementation (7.5g) improved glucose tolerance and reduced HbA1c levels

A summary of the key preclinical and clinical findings on GLP-1RAs and DPP-4is in neuropathic pain models is presented in Table 1, highlighting their proposed mechanisms of action and therapeutic outcomes across various studies

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48 h) significantly reduces high glucose (HG)-stimulated production of fibronectin, collagen type IV, and -smooth muscle actin in human mesangial cells

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Most GLP-1RA CVOTs incorporated secondary exploratory renal endpoints
