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When to Startand When Not To According to the package insert, GLP-1 therapy for obesity is indicated for individuals with a BMI 27 with a weight-related condition, or a BMI 30 alone

That is the trap: tirzepatide is not a treatment you finish it is a lifetime subscription

The eGFR increase in the obesity trial was accompanied by a significant UACR decrease in the retatrutide group, suggesting that the increase in glomerular filtration was accompanied by a lower intraglomerular pressure and kidney stress

These findings have led to ongoing clinical trials investigating GLP-1-based therapies for alcohol use disorder and other substance use conditions

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This article explores evidence-based guidance on fibre intake for patients taking GLP-1 therapy, aligned with NHS and NICE recommendations, to improve tolerability and long-term adherence