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One cohort study published in JAMA in November 2025 found that those who halted GLP-1 use before or early in their pregnancies gained more weight and had higher risks of pregnancy complications like hypertensive disorders, diabetes and preterm delivery compared to those who hadnt used the medications before

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Because it acts differently from most antidepressants, many people find it helpful when theyre looking for mental health support without the side effects like fatigue or weight gain

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