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Diabetes is a complex disease that requires not only adherence to medications (including insulin regimens and oral drugs) but also to diet, physical exercise and home glucose monitoring, among others

9-13 In two of the trials, there was a significant association between the use of a synthetic GLP-1/GIP agonist and worse eye-related outcomes

In addition, more phase II and phase III studies are underway to further assess the role of these agents in managing the disease

We refuse to be strong-armed by any pharmaceutical companys anticompetitive demands that infringe on the independent decision making of providers and limit patient choice," Dudum said in a statement to Fierce Healthcare

The FDA label includes specific guidance on dose titration schedules to minimize gastrointestinal adverse effects during initiation

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