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PMID: 30 JinT

You may face additional questions if you're also taking insulin, anticoagulants, or other medications

Are not prepared for potential gastrointestinal side effects: GLP-1 medications commonly cause nausea, vomiting, diarrhea, and constipation, particularly during dose escalation periods

In gastrointestinal inflammatory conditions , observational data suggest that GLP-1RA use in patients with inflammatory bowel disease is associated with a lower risk of IBD-related surgery in both ulcerative colitis and Crohns disease, and early studies have explored whether GLP-1RA injections can reduce pain in irritable bowel syndrome patients (the answer was yes)

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Examples include a Phase II study, NCT02028221, designed to determine whether metformin reduces obesity-associated breast cancer risk and due to be completed in mid-2021