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The uncoupling of Mitochondria-ER Contact Sites (MERCS) represents a hallmark of metabolic dysfunction in obesity and type 2 diabetes

McDonalds is the latest fast-food chain to jump on the GLP-1 train, testing new menu items to appeal to growing swaths of customers on the popular weight-loss drugs.

Management is primarily dietary, focusing on small, frequent meals and low-glycemic index foods to stabilize glucose levels

The company known for its festive fruit baskets just launched a new website for hemp-derived, THC-infused beverages and gummies.

These actions have been clinically exploited by the development of amylin and GLP-1 hormone analogs now used for treatment of diabetes and obesity

In other words, metformin isn't just a glucose-lowering drugit's a top-down rewiring agent for gut nutrient sensing and hormone modulation, which likely underlies the benefits observed across so many organ systems