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(1997) Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues

13 Given these multiple actions, in pediatric models, GLP-1R activation may directly interfere with metabolic plasticity, cellular differentiation, and tissue remodeling, requiring caution regarding potential off-target effects during growth and development

Tirzepatide , a dual GLP-1/GIP receptor agonist, has been approved by NICE for type 2 diabetes management