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Taken together, these findings highlight the potential therapeutic value of adding GLP-1RA to SGLT2i as a novel treatment strategy for patients with MASLD

Partial agonism at GPCRs is not inherently disadvantageous and can, in some contexts, confer therapeutic benefits

Monami M., Nreu B., Scatena A., et al., Safety Issues With GlucagonLike Peptide1 Receptor Agonists (Pancreatitis, Pancreatic Cancer and Cholelithiasis): Data From Randomized Controlled Trials, Diabetes, Obesity and Metabolism 19, no

Contraindications Personal/family history of medullary thyroid carcinoma

For complete prescribing information, please refer to the package insert available here

It is important to document baseline weight at the time the medication is started , as insurers often compare renewal weight to the original starting weight