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glp-1 receptor agonist mechanism of action Frontiers List of GLP-1 Receptor Agonists
Description
Glucagon promotes satiety and increases energy expenditure in humans

Bariatric surgery was associated with greater weight loss, but GLP-1 RA therapy was associated with better outcomes

The long-acting compounds have insulinotropic and glucagonostatic actions, and exert their main effect on fasting glucose levels [27-29]

Mahalingam S, Bellamkonda R, Arumugam MK, Perumal SK, Yoon J, Casey C, et al

doi: 10.1038/nature05485
doi: 10.1038/bjp.2008.100 97 WebsterLRReisfieldGMDasguptaN
