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Abbreviations GLP-1: Glucagon-like peptide-1 GLP-1RA: Glucagon-like peptide-1 receptor agonist T2DM: Type-2 diabetes mellitus DPP-4: Dipeptidyl peptidase 4 HbA1c: Hemoglobin A1c NASH: Non-alcoholic steatohepatitis NAFLD: Non-alcoholic fatty liver disease Camp: Cyclic adenosine monophosphate PKA: Protein kinase A EPAC: Exchange protein directly activated by cAMP PI3K: Phosphoinositide 3-kinase PYY: Peptide YY CCK: Cholecystokinin GLUT4: Glucose transporter type 4 mTORC1: Mammalian target of rapamycin complex 1 References Ahrn B (2015) Hepato-incretin function of GLP-1: novel concept and target in type 1 diabetes

The rapid rate of weight gain has also been implicated in the development of IIH

The researchers analyzed thousands of electronic medical records of older adults with both diabetes and cancer and found that those who were taking GLP-1s had lower all-cause mortality than did those who were taking another type of diabetes medication, dipeptidyl peptidase 4 inhibitors (DPP-4i)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 29.Rosenstock J., Raccah D., Kornyi L., et al

It often improves or helps prevent obesity-related diseases, including type 2 diabetes, sleep apnea, high blood pressure, and fatty liver disease