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Safety and Efficacy of Glucagon-Like Peptide-1 Receptor Agonists Use in Elderly People With Obesity A Meta-Analysis

hospitalization for heart failure in patients with type 2 diabetes mellitus and either established cardiovascular disease (CVD) or multiple cardiovascular (CV) risk factors

Perspectives and conclusions Tirzepatide has demonstrated marked and dose-dependent reductions in glycemic parameters in patients with T2D that, according to the present study data, surpass the effects of the GLP-1RA dulaglutide and semaglutide (54, 66, 67, 71)

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While the inherent pharmacokinetic properties of each GLP-1 receptor agonist largely determine elimination time, several patient-specific factors can influence how quickly or slowly these medications clear from the body