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Additionally, GLP-1 activates related intracellular signaling pathways, promoting -cell regeneration, inhibiting -cell apoptosis, and improving -cell function, thereby lowering blood glucose levels, with its effects being glucose concentration-dependent (58, 59)

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But as researchers at Yale have pointed out, patients pursuing unvalidated microdosing protocols are essentially serving as their own test subjects on both efficacy and safety

[DOI] [PMC free article] [PubMed] [Google Scholar] 85.Chen X., Huang Q., Feng J., Xiao Z., Zhang X., Zhao L

Pyke C, Heller RS, Kirk RK et al (2014) GLP-1 receptor localization in monkey and human tissue: novel distribution revealed with extensively validated monoclonal antibody