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Its FDA-approved under different names for: Type 2 diabetes management (Ozempic) Chronic weight management (Wegovy) Its typically administered via a once-weekly injection and has shown substantial weight loss results in clinical studies

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In a large analysis using the TriNetX database including 15,176 propensity-matched pairs of patients with type 2 diabetes and MASLD, initiation of GLP-1 receptor agonists was associated with a significantly lower risk of composite MALOs compared to sodium-glucose cotransporter 2 inhibitors (adjusted hazard ratio [aHR] 0.84) [131]

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