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Cleavage of a gastric inhibitory polypeptide with cyanogen bromide and the physiological action of the C-terminal fragment

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The patent includes only two specific compounds in its examples, with the primary difference being the substitution of a carbon atom on the indole ring with a nitrogen atom

The addition of multiple GLP-1 receptor agonists to the National Reimbursement Drug List (NRDL) as part of Chinese government negotiations in 2019-2022 greatly enhanced access to these drugs, lowering the out-of-pocket cost by 60-80% and putting the drug into 200-300% use in 12-18 months of listing

Pricing Breakdown Sheds pricing varies by medication format