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Perhaps even more unsettling were the ads for telehealth company Ro that played throughout the season, specifically highlighting its weight loss expertiseeven as one of the shows central figures opened up about her issues with GLP-1s

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Patients with a personal or family history of medullary thyroid carcinoma (MTC) or patients with multiple endocrine neoplasia syndrome type 2, the GLP-1 agonist are CONTRAINDICATED

In addition to providing long-term weight loss and possibly remission of T2DM, bariatric surgery is not feasible for large populations, has specific indications, and may result in surgical complications as well as other issues like malabsorption and micronutrient deficiencies

The medications impact on mental health appears complex, with some evidence suggesting possible benefits through reduced inflammation and improved brain health