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In a small RCT, exenatide significantly lowered ICP within hours of administration

Stopping GLP-1 medications before surgery requires careful planning

Those who discontinued had an increased risk of heart attack and stroke compared to those who remained on treatment.

At a GlanceElecoglipron is AstraZenecas oral GLP1 candidate for type 2 diabetes and weight management.SOLSTICE Phase IIb: primary HbA1c endpoint met at 26 weeks.VISTA Phase IIb: both weightloss coprimary endpoints met at 26 weeks.Data support advancement toward Phase III as an oral alternative to injectable GLP1 therapies.Written By: Pharmacally Medical News DeskAstraZenecas investigational oral GLP1