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The medication itself is rarely the direct cause

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Ligand-independent actions of estrogen receptors (ERs) have also been described, particularly in the uterus, where ER can be activated by growth factor pathways (e.g., IGF-1), leading to receptor recruitment to chromatin in the absence of estrogen binding (Meyer et al., 2011

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Bloomberg reported that Aspen sees GLP1s as a durable long-term growth driver and that Stephen Saad expects semaglutide generics to attract 12 to 15 manufacturers, with intensifying price competition

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