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The primary composite endpoint non-fatal myocardial infarction, non-fatal stroke or cardiovascular death occurred in 6.5% of the semaglutide arm versus 8.0% of the placebo arm

Another trial ( n = 30) using the same dosing and duration reported a similar benefit, with an estimated treatment difference of 7.8 kg ( 7.7% in body weight) in favor of semaglutide [168]

And it was, it was just, again, it was a terrible way to live

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Other classes are added depending on patient profile (obesity, CV disease, kidney disease, hypoglycemia risk)