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Importantly, injectable therapies such as WEGOVY and ZEPBOUND are unlikely to lose relevance

Contact your GP or diabetes care team if you experience: Severe or worsening cognitive symptoms that interfere with daily activities, work, or safety Symptoms of hypoglycaemia including confusion, shakiness, sweating, rapid heartbeat, or difficulty speakingparticularly if recurrent Persistent brain fog lasting beyond the first few weeks of treatment or following a dose increase New neurological symptoms such as severe headaches, visual changes, weakness, numbness, or difficulty with speech or coordination Signs of dehydration including dark urine, dizziness, dry mouth, or reduced urination Mood changes including depression, anxiety, or unusual thoughts Inability to keep fluids down for 24 hours or severe, persistent vomiting Seek urgent medical attention (call 999 or attend A&E) if you experience severe confusion, loss of consciousness, seizures, or any symptoms suggesting a stroke or other acute neurological event

That is the kind of number that, in any other context, would already be driving clinical guidelines. Kamat and her team found even higher cancer risk reductions in specific cancers, including a 58% lower risk of endometrial cancer

Biochem Biophys Res Commun 472(1):201208 Read NW, McFarlane A, Kinsman RI, Bates TE, Blackhall NW, Farrar GB et al (1984) Effect of infusion of nutrient solutions into the ileum on gastrointestinal transit and plasma levels of neurotensin and enteroglucagon

These benefits may be attributed to their anti-inflammatory, antioxidant, and neuroprotective properties, as well as improvements in brain energy metabolism ( 3.3 Renal protection Yin et al
