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In the SURMOUNT-1 trial, patients lost up to 20% of body weight at higher doses, making it the most effective option available to date

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Many people simply describe palpitations as a general feeling of unease

The most clinically useful research will come from prospective studies that specifically enroll autoimmune patients starting tirzepatide for metabolic indications and track autoimmune disease activity alongside metabolic outcomes

Cardiovascular disease, uncontrolled hypertension, glaucoma, hyperthyroidism, and history of substance abuse all contraindicate its use

For individuals vulnerable to disordered eating, that combination can be combustible