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Description
The intranasal administration of peptides for treating a disorders originating in the brain is not a novel concept, but only the vasopressin analog desmopressin has been used clinically by this route for several decades to treat diabetes insipidus (Kastin and Pan, 2012)
TRIUMPH-1 ran as a master protocol: an 80-week, randomized, double-blind, placebo-controlled study in 2,339 adults with obesity or overweight and without diabetes
It is crucial for various bodily functions, particularly in maintaining a healthy nervous system , producing red blood cells , and supporting DNA synthesis
A phase 2 trial on pegylated exenatide (NLY01) was negative for motor and non-motor measures, with subgroup analysis suggesting potential motor benefit in younger individuals [167]
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