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In the context of elective surgical procedures, metformin should be discontinued 24 h prior to the intervention and resumed 48 h postoperatively, provided that renal function remains stable [70]
Turning cold tumors hot: from molecular mechanisms to clinical applications
It functions by mimicking the body's GLP-1 hormone to regulate blood sugar
doi: 10.1016/j.pharep.2015.10.008 44 ShiraishiDFujiwaraYKomoharaYMizutaHTakeyaM
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Steady state is the point where the repeated input and the compound clearing from the system reach a predictable pattern
