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51 Rates of genital infection, predominately vulvovaginal candidiasis amongst women, appear modestly increased in most studies by 2.0%8.9% when compared to placebo

Similarly, cutting or modifying patches to adjust dosing is dangerous and should never be attempted, as this can cause rapid, uncontrolled drug release and potential overdose
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However, dedicated kidney outcome trials for GLP-1 receptor agonists remain limited, and further long-term studies are needed to better define their role in CKD management

Association between exposure to GLP-1 receptor agonists and risk of suicide-related and self-harm-related events
Nauck MA, Mller TD
