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2023 ESC Guidelines for the management of cardiovascular disease in patients with diabetes: developed by the task force on the management of cardiovascular disease in patients with diabetes of the European Society of Cardiology (ESC)

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Scand J Gastroenterol 2009

Trial design itself is another determinant

Its sister drugs, Wegovy and Rybelsus, are also semiglutide drugs that are FDA-approved for weight loss

Contrave works in the brains hypothalamus to reduce hunger, and in the mesolimbic reward system in the brain, to reduce food cravings
