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Description
Am J Med 2000;109:307e14
In the US, the prevalence of melatonin use for sleep disorders among individuals 65 or older increased from 0.6% in 1999 to 2.1% in 2018, with a similar rise in use in UK
Why is this a problem
108 In one trial included in the meta-analysis, 60 women with PCOS received 500 mg curcumin or placebo twice daily for six weeks
The clinical trials that showed the lowest nausea rates used the slowest titration schedules
Weight fluctuations of 2 to 4 pounds daily are completely normal and reflect water, sodium, and digestive contents rather than true fat changes
