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Nature (1997) 389(6651):6104.10.1038/39335 95 GagnonJSauvMZhaoWStaceyHMWiberSCBolzSSet alChronic exposure to TNFalpha impairs secretion of glucagon-like peptide-1

These effects correlated with reduced crypt cell apoptosis, as indicated by decreased cleaved caspase-3 staining

Some patients eventually reach maintenance doses of 1.7mg or 2.4mg depending on their response and tolerance
C., Ip, B., Wing, Y
