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doi: 10.1074/jbc.M609088200

Nonarteritic anterior ischemic optic neuropathy: epidemiology, pathogenesis, and etiologies

GLP1s+ Summary In the last 30 years, weve gone from no GLP1s+ or truly scalable weight loss treatments to having treatments that: Efficacy: help patients lose 22% (and still rising) of their weight on average, up from 3-5% Disease Expansion: are approved for diabetes, obesity, cardiovascular disease and soon likely kidney disease and sleep apnea, with more conditions under study Frequency: are taken 1x/week, down from 2x/day (52 times per year versus 730) Form Factor: can be taken orally with more effective options on the horizon Improving the form factor, reducing the burden placed on the patient, all while maintaining and increasing efficacy across weight loss and other cardiometabolic measures, these are incredible feats of science that will benefit humanity in ways we cannot yet comprehend, especially once prices decline

With the savings car, patients can pay as little as $25 for a 1 month or 3 month supply of Mounjaro

The dulaglutide molecule consists of two modified DPP-4 resistant GLP-1(7-37) peptides fused to a modified IgG4 Fc fragment, which protect dulaglutide from proteolytic degradation by DPP-4 (132)

"Better" depends entirely on the research question
