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While observational data cant prove causation on its own, seeing a graded relationship like this suggests that prolonged exposure could play a role in increasing risk

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Individual timing varies based on body composition, metabolism, and GLP-1 receptor sensitivity

CSF Levels of Dopamine and Serotonin, but Not Norepinephrine, Metabolites Are Influenced by the Ketogenic Diet in Children with Epilepsy. Epilepsy Research, vol
