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After a median follow-up of 2 years, the incidence of new or worsening nephropathy in the semaglutide group was lower than that in the placebo group [HR 0.64 (95% CI: 0.460.88, p=0.05)]

The following statements reflect emerging research headlines and do not guarantee individual outcomes

Inhibition of DPP4 using a DPP4 inhibitor or glucagon-like peptide 1 (GLP-1), both incretin-based therapies, has shown protective effects against fibrosis and dysfunction in rodents (16)

The delayed emptying effect is most pronounced during the first few hours after taking semaglutide, especially at higher doses

This latter finding is in accordance with prior research that linked intermittent fasting to both reduced LV mass in mice [13] and to improved LV ejection fraction in patients after ST-segment elevation myocardial infarction [14]