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For the injectable side of that comparison, see our breakdown of whether tirzepatide is a peptide

This includes a full telehealth consultation, personalized care plan, and if eligible, your first shipment of medication

JAMA 2021;325:1414-25.PubMed 117

In particular, His7 (in the N-terminus of GLP-1) has a free alpha-amino group and an imidazole side chain that are important for the GLP-1R/GLP-1 interaction18)

They are potent stimulators of postprandial insulin secretion under hyperglycemic conditions and contribute to approximately 70% of the physiological postprandial insulin secretion