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The most common neurological side effects are headache (8-14% of patients) and dizziness (4-8% of patients), which are typically mild to moderate and often resolve with continued treatment
FDA Safety Reports Analyzed To investigate the potential connection, researchers reviewed reports submitted to the US Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) between December 2017 and December 2024

Bkdal TA, Borregaard J, Donsmark M, Breitschaft A, Sndergaard FL

Two things can help prevent muscle loss on semaglutide

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demonstrated GHS-R1a mRNA expression in GLUTag and NCI-H716 cells (30)
