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Access and Equity Considerations The high cost of GLP-1 RAs raises major concerns about health equity and access

For tirzepatide, the gastric emptying effect is most pronounced after the first dose and tends to diminish with continued treatment, a phenomenon known as tachyphylaxis

With a pause on shipments of its Gardasil HPV vaccine to China, once a major growth market for the product, investors were spooked despite the company continuing to drive growth from the blockbuster checkpoint inhibitor Keytruda (pembrolizumab) as it expanded market share and reached new oncology indications
