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PMID 30780817

Itching and rashes can make it uncomfortable to wear certain clothes, engage in physical activities, or concentrate on tasks

Patients can reduce their risk by avoiding excessive alcohol consumption and speaking with their healthcare provider if they experience persistent abdominal pain

And some government programs are also changing how they handle things

Since this is a new delivery platform of existing drugs rather than a new drug, the regulatory bodies in many jurisdictions typically have alternative, shorter approval pathways available to drug sponsors that do not require the standard Phase I-III clinical trials for a new drug application

The exact impact depends on the temperature and duration, but erring on the side of caution with room temperature storage limits protects your investment