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RELEVANCE: Older adults are at higher risk of frailty, sarcopenia, dehydration, and nutritional decline

Benefits, dosing, and safety considerations.

Discover how medications like Ozempic and Wegovy may reduce joint symptoms through weight loss and potential anti-inflammatory effects

Both medications are designed for once-weekly dosing, but retatrutides triple-receptor targeting (GLP-1, GIP, and glucagon) may result in faster and more pronounced outcomes compared to tirzepatides dual-receptor mechanism (GLP-1 and GIP)

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It summarizes the 2023 NEJM data and walks through sourcing and protocol design for Canadian researchers