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Wang XF, Liu JJ, Xia J, Liu J, Mirabella V, Pang ZP

Bone 95 , 4754 (2017)

Clinically, GLP-1RAs like semaglutide induce sweet hyposensitivity and reduce preference for hyperpalatable foods, an effect mediated by changes in endogenous GLP-1 secretion and synaptic plasticity in reward circuits (166)

Women on both therapies in the 2024 semaglutide study lost significantly more weight than those on semaglutide alone at every measured checkpoint

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