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Description
They reduce appetite
For the assessment of the changes from baseline following GLP-1-based therapies in % FMD and IMT, mean differences with 95% confidence intervals (CI) were calculated between baseline samples and end-of-treatment samples for each study and then an overall effect size was generated

Projected US state-level prevalence of adult obesity and severe obesity
Many users experience appetite rebound and weight gain within 3-6 months of stopping GLP-1 medications, though the amount varies individually and depends on diet, activity level, and genetic factors

2021;38:e14525

These medicines are typically administered by subcutaneous injection, though oral formulations of semaglutide are also available
