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Clinically, GLP-1RAs could lead to an improvement in cognitive function, which is often found to be impaired across several conditions such as psychosis 240 and mood disorders 241 , eventually leading to an overall benefit as observed in some of the included studies (Tables 4 and 5)

ClinicalTrials.gov (2017)

Consequently, the immunological impact of the new antidiabetic drugs (SGLT2i and GLP1-RAs) looks very relevant

Fact: Most people with a history of the condition can take them, provided they are not in an active flare and have a plan to manage constipation

Business Group on Healths 2026 survey found nearly 8 in 10 employers say GLP-1s are driving up their health care costs

Several studies suggest that similar to lipids, reductions in food intake via intestinal protein in rodents are due to CCK release and subsequent activation of VANs, as (1) intestinal protein infusion increases CCK in rodents and humans 188,189