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GLP-1 agonists/analogues show beneficial effects on most of the multiple alterations underlying MASLD and cirrhosis progression [10]

MWN-109 is a synthetic peptide in Phase 2 since August 2025, with a concurrent Phase 1b MAD study

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Persistence remains mixed: a 2024 real-world study found 32% on therapy at 1 year among non-diabetic users, and according to Prime Therapeutics, only 1 in 12 remain at 3 years

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In situ hybridization has identified Glp1r expression in type 2 alveolar epithelial cells, which may contribute to Il6 and Ccl2 induction following bleomycin exposure (77)