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Description
The pooled outcomes for tirzepatide showed a more significant positive impact in each individual lipid measure as compared to semaglutide in a population with similar baseline characteristics

it activates both GLP-1 and another hormone known as GIP (glucose-dependent insulinotropic polypeptide)

Increased FFA in the liver results in insulin resistance, hepatic glucose production, and pancreatic beta cell dysfunction [7]

PMID: 28448947 Drucker DJ (2022): GLP-1 physiology informs the pharmacotherapy of obesity

Zepbound can help manage blood sugar but cannot eliminate the risk of diabetes if it is inadequately controlled

2025;4:ehae938