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More extensive clinical trials are needed to shed more light on the effectiveness of retatrutide for T2D, and whether it may be limited due to the activation of the GCG receptors, which may exert anti-insulin effects

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[1] For weight management, Zepbound is indicated as an adjunct to reduced-calorie diet and increased physical activity for adults with either a BMI of 30 kg/m or greater (obesity), or a BMI of 27 kg/m or greater (overweight) in the presence of at least one weight-related comorbid condition

Mounjaro is a treatment for type 2 diabetes (T2D)