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Semiglutide is associated with Ozempic, Wegovy, and Rubelsus, affecting GLP1S

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Could the gut microbiome be playing a hidden role in both the benefits of GLP-1s as well as constipation?

ICH-compliant GLP toxicology report available.

Research design and methods Using the data from the United States Food and Drug Administration Adverse Event Reporting System (FAERS) and Japanese Adverse Drug Event Report (JADER) databases, the differences in adverse events across specific subgroups concerning reporter type, sex, age, dose, indication, report year, onset time, and outcome were investigated using the ROR algorithm and Chi-Square Test/Fishers exact test