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The observations that GLP-1 receptor agonists exert anti-inflammatory actions in preclinical studies, taken together with case reports linking improvements in psoriasis with GLP-1 receptor agonist therapy, illustrates the emerging clinical implications of non-classical anti-inflammatory actions of incretin-based therapeutics.

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One of the most vexing issues in the field of inflammation research pertains to how the very bacteria and cells in the intestine that are required for host survival can also induce life-threatening inflammation

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