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The lipotoxicity of FFA contributed to the downregulation of hepatic GLP-1R, which led to hepatic unresponsiveness to GLP-1 and disease progression

Observational studies using linked electronic health records, prescription databases, or ambulatory BP monitoring can assess treatment patterns, adherence, and comparative effectiveness and safety across more heterogeneous and underrepresented populations

Immunology 172, 451468

Davenport)
Genetic determinants of weight loss after bariatric surgery

The metabolic protection of maintained muscle mass becomes the primary defense against the caloric surplus that drives weight regain
