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The lipotoxicity of FFA contributed to the downregulation of hepatic GLP-1R, which led to hepatic unresponsiveness to GLP-1 and disease progression

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Observational studies using linked electronic health records, prescription databases, or ambulatory BP monitoring can assess treatment patterns, adherence, and comparative effectiveness and safety across more heterogeneous and underrepresented populations

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Immunology 172, 451468

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Davenport)

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Genetic determinants of weight loss after bariatric surgery

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The metabolic protection of maintained muscle mass becomes the primary defense against the caloric surplus that drives weight regain

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