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Description
The glucagon-like peptide-1 (GLP-1) is a pleiotropic hormone well known for its incretin effect in the glucose-dependent stimulation of insulin secretion

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Melanocortin 4 receptor (MC4R) is a G-protein-coupled receptor expressed in the hypothalamus, playing a key role in regulating feeding behavior and energy homeostasis

Rybelsus and Farxiga treat Type 2 diabetes, but one has more approved uses, among other differences, such as cost and side effects.

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Histograms show AUC0510 min for with respect to (b) hunger and (d) fullness [1]