how do glp 1 agonists work for diabetes Mechanism of action of GLP-1 [25] Current Insights, Advantages and Challenges

It is considered a controlled substance that can be addictive and carries the risk of withdrawal symptoms and potential side effects such as a racing or irregular heartbeat

Gromada J, Franklin I, Wollheim CB

The high cost of these drugs creates hurdles to access and fair healthcare

The deal with Eli Lilly and Novo Nordisk is set to expand Medicare coverage of Zepbound and Wegovy, two GLP-1 receptor agonist medications

While Mounjaro has marketing authorisation for these indications, NHS availability is determined by NICE guidance

However, the use time and effect of GLP-1RAs, and the adverse reactions after long-term use must also be fully paid attention to and studied before clinical application