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Cell Transplant 29:963689720927392 Peters CT, Choi YH, Brubaker PL, Anderson GH (2001) A glucagon-like peptide-1 receptor agonist and an antagonist modify macronutrient selection by rats

When asked why, the most common reasons cited included not knowing enough about the long-term side effects of these drugs (49%), these medications being overused (32%), beliefs that weight loss should be managed by lifestyle not medication (29%), and feeling that the people who really need these medications arent getting them because too many people are using them for purely cosmetic purposes instead of health reasons (21%)

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[DOI] [PubMed] [Google Scholar] 41.Giugliano D., Scappaticcio L., Longo M., Caruso P., Maiorino M.I., Bellastella G., Ceriello A., Chiodini P., Esposito K

In clinical trials, participants taking the highest dose of orforglipron lost up to 15% of their body weight by week 72