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Large, heavy meals Overeating can overwhelm the stomach, leading to discomfort
Lomaira is for adults with an initial BMI* of 30 or more (obese) or 27 or more (overweight) with at least one weight-related medical condition such as controlled high blood pressure, diabetes, or high cholesterol

Neither mechanism directly stimulates insulin secretion in a glucose-independent manner, making the combination inherently safer regarding hypoglycaemia compared to sulphonylureas or insulin

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